Single-Use Pressure Sensors
Single-Use Pressure Sensors for Bioprocessing | Pendotech
Monitor Pressure in Your Bioprocess with Confidence
Pendotech’s Single-Use Pressure Sensors™ for bioprocessing provide accurate and cost-effective pressure measurement for both gases and liquids in biopharmaceutical processes. Whether you need to track static pressure in a filtration system or dynamic pressure in a disposable bioreactor, these sensors are designed to adapt to your workflow.
Why Choose Single-Use Pressure Sensors?
- Accurate and Reliable: Equipped with MEMS-HAP™ high-accuracy pressure chips for consistent readings across your process.
- Cost-Effective: Affordable enough for disposable pressure measurement for biopharma applications, yet robust for repeated cleaning.
- Versatile Applications: Perfect for filtration, chromatography, gas monitoring, disposable bioreactors, and filling operations.
- Sanitization Ready: Made from caustic-resistant polysulfone, compatible with common cleaning processes.
Integration & Compatibility
Pendotech sensors are compatible with multiple monitoring systems:
- PressureMAT™ System – Monitor and transmit pressure data in real-time.
- Pendotech Process Control Systems (PCS) – For automated multi-sensor setups.
- Third-Party Monitors – Pre-qualified integration with selected systems.
Rated for use up to 75 psi, these sensors provide flexibility and reliability for small- to medium-scale biopharmaceutical processes.
Applications in Bioprocessing
Pendotech sensors are ideal for inline pressure monitoring for scenarios such as:
- Filtration & chromatography systems
- Gas monitoring in disposable bioreactors
- Filling operations and small-scale production workflows
- Other applications requiring precise pressure measurement in biopharmaceutical processes
Pendotech pressure sensors help you:
- Monitor pressure in single-use bioprocessing without stainless transducers
- Maintain tight control during filtration, TFF, or bioreactor operations
- Reduce hold-up volume and protect product yield
- Integrate seamlessly with existing monitoring or control systems
- Simplify QA and compliance with fully tested, USP Class VI materials
Additional Products
Pendotech Single-Use Pressure Sensors are designed for teams running small- to mid-scale bioprocessing workflows who need accurate, low-hold-up, single-use pressure monitoring that integrates seamlessly with a PressureMAT™ System (monitor/transmitter), Pendotech Process Control System (PCS), or third-party pumps and monitors.
When to Choose a Pendotech Pressure Sensor
Best for scenarios like:
- When you need pressure monitoring during depth filtration or TFF/crossflow filtration
- When a single-use, sterilizable sensor is required
- When your tubing runs from 1/8 inch to 1.5 inch ID
- When you need ‐7 to 75 psi measurement accuracy in flexible tubing
- When minimizing hold-up volume is critical to yield
- When you must integrate with existing pumps, controllers, or PAT systems
How the Sensors Integrate into Your Process
Pendotech pressure sensors can connect to:
- PressureMAT™ System
For teams needing a compact monitor/transmitter with alarms.
- Pendotech Process Control System (PCS)
For multi-sensor setups or automated control.
- Third-Party Pumps & Monitors
Pre-qualified for easy drop-in integration.
Outputs:
Data can be sent to a PC or any external monitoring device (PC output comes from PMAT or PCS, not directly from the sensors).
Common use cases
- Multi-stage depth filtration – consistent pressure tracking across filter trains
- TFF / crossflow filtration – maintain TMP without traditional stainless transducers
- Bioreactor pressure monitoring – sterile, single-use compatible
- General upstream & downstream bioprocessing
Compatibility & Operating Ranges
- Pressure range: –7 to 75 psi
- Tubing sizes: 1/8 inch to 1.5 inch ID (luer option available)
- Sterilization: Gamma & x-ray irradiation compatible
- Documentation: Validation guide available
Design & Performance Features
- Unobstructed flow path & no dead legs provides dramatically reduced hold-up volume versus stainless steel transducers or gauges
- Integral 12-inch cable connects to reusable monitor/ transmitter/alarm cable via molded connector
- Suitable for tubing from 1/8 inch to 1.5-inch inner diameter (luer size available separately) or a sanitary flange
Design & Performance Features
Minimal Hold-Up Volume
Unobstructed flow path + no dead legs → reduces product loss during small-scale runs.
Integrated 12-inch Cable
Connect directly to a reusable monitor/transmitter/alarm cable.
Flexible Connection Types
- Direct tubing (1/8–1.5 inch)
- Luer (ordered separately)
- Sanitary flange
Materials, QA, and Compliance
Construction
- Polycarbonate or caustic-resistant polysulfone
- All materials meet USP Class VI
Manufacturing & QA
- Built in an ISO 9001–certified clean room
- Each sensor tested – rejected if out of specification
- No calibration required
Documentation
- Certificate of Conformanceincluded
- Optional NIST calibration certificate
Hose Barb Design: Preventing Leaks
This design reduces the chance of tubing leaks by eliminating a mold parting line.
Why it matters:
- Single barb shaft lets the hose relax behind the barb for a secure drawstring effect
- Anti-rotation device holds tubing in place during twisting or repositioning
For higher-pressure needs:
- BarbLock
- Oetiker clamp
- Both provide 360° radial compression sealing
Sensors for Smaller Scale Processes (Luer Models)
Ideal for applications like:
- Low-flow in-line monitoring (1/8 inch)
- Dead-end measurements using included cap
- Adaptation to 1/4- or 3/8-inch barb fittings with luer ports
Sterility – Polycarbonate version ships sterile for aseptic setups.
Data & Technical Tables

* Data from 100 random sensors manufactured with the PendoTECH High Accuracy Pressure chips (MEMS-HAP chips) and measured with the Pendotech Process Control System.
BarbLock® is a registered trademark of Saint-Gobain Performance Plastics Corporation all rights reserved.

Adaptor Cables for Third Party Monitors
- PDKT-650-298SC – Reusable shielded 6 ft connector cable w/ phone jack for Scilog pumps
- PDKT-650-298MG – Reusable shielded 6 ft connector cable w/phone jack for Midgee monitor
- PDKT-650-298MN – Reusable shielded 6 ft connector cable w/ phone jack for Pall Minim
Fittings
- PDKT-103-03 – 1/4 inch x 1/4 inch polycarbonate straight connector with luer port
- PDKT-104-03 – 3/8 inch x 3/8 inch polycarbonate straight connector with luer port
- PDKT-105-03 – 1/ 2inch x 1/2 inch polycarbonate straight connector with luer port
- PDKT-V3PS-000 – Luer polysulfone 3-way stopcock
- PDKT-650-298 – Reusable shielded connector 12 ft cable for sensor w/ colored leads
- PDKT-650-298BH – Bulkhead connector for panel mount connection of Pendotech Pressure & Conductivity Sensors
- PMAT-EXT-12F – Pressure senor extension cable (12ft)
- PDKT-650-298CVR – Pressure sensor cable dust cover/zero simulator for PressureMAT
Data Sheets
- Single-Use Pressure Sensor Data Sheet
- Single-Use Pressure Sensors for Use in Flexible BioProcess Containers Data Sheet
- Pendotech cable adaptor for Single-Use Pressure Sensor – PDKT-650-298
Technical Notes
Product Guides
Technical Instructions
- Panel mount connection of Pendotech Pressure & Conductivity Sensors- PDKT-650-298BH
- Technical Note: Pressure Sensor Materials
- Pendotech Single-Use Pressure Sensors: Calibration, Accuracy, and Implementation
- Pendotech Sensor Chemical Compatibility
- Technical Note: Pendotech Sensors and Industry 4.0: Integrating a Pendotech Single Use Sensor System with a Digital Highway
Application Notes
- Application Note: Versatile Sensor Solutions
- Application Note: Peptide Bioprocessing Purification Using Advanced Flow and Pressure Sensors
- Application Note: Pendotech Single-Use Pressure Sensors™: For Single Use and Glass Bioreactor Monitoring and Control
- Application Note: Preliminary X-Ray Irradiation Evaluation
- Application Note: Autoclave
- Application Note: Short Term NaOH Compatibility
- Enhancing Recombinant Vaccine Production with Single-use Sensors Application Note
- Greater Depth Filtration Performance Through Turbidity and Pressure Monitoring Application Note
- Enhancing Biotherapeutics Safety Application Note
- Improve Perfusion Cell Culture with Controlled Pressure and Flow Rate Application Note
Articles
- “Single-Use Pressure Sensors for Continuous Processing and Leak Testing” – Dennis Annarelli, PhD, Mark Marrano, Josh Huang, and Jim Furey- Genetic Engineering News, (Sept 2018)
- “Single-Use Noninvasive Sensing Technology” – Jim Furey – Genetic Engineering News, (July 2009)
- “Using In-Line Disposable Pressure Sensors to Evaluate Depth Filter Performance” – Lee R. Bink and Jim Furey – BioProcess International 8(2), (February 2010)
- “Measuring Pressure at Very Low Levels with High Accuracy in Single-Use Systems” – Dennis C. Annarelli, Jim Furey, Benjamin Less, and Joshua Huang – BioProcess International 13(3)s, (March 2015)
* Please contact your local Pendotech representative for a quote.


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