Frequently Asked Questions (FAQs)

What is a single-use pressure sensor in bioprocessing?

A single-use pressure sensor is a disposable sensor used to measure gas or liquid pressure in biopharmaceutical processes. It eliminates cleaning and revalidation while providing accurate, real-time pressure data in filtration, bioreactors, and downstream operations.

How are single-use pressure sensors used in biopharma manufacturing?

Single-use pressure sensors are commonly used in filtration systems, disposable bioreactors, chromatography skids, gas monitoring, and filling operations. They support real-time monitoring and help maintain process control in GMP environments.

What are the benefits of single-use pressure sensors compared to traditional sensors?

Compared to traditional reusable sensors, single-use pressure sensors reduce contamination risk, shorten setup time, eliminate cleaning validation, and simplify changeovers—making them ideal for flexible and fast-moving bioprocess workflows.

Can single-use pressure sensors be integrated with existing monitoring systems?

Yes. Pendotech single-use pressure sensors integrate with the PressureMAT™ (PMAT) System, Pendotech Process Control Systems (PCS), and selected third-party monitoring platforms for seamless real-time data collection.

Are Pendotech single-use pressure sensors compatible with GMP processes?

Yes. Pendotech single-use pressure sensors are designed for biopharmaceutical GMP manufacturing and are made from biocompatible, caustic-resistant materials suitable for cleanroom and regulated environments.

Can pressure sensors be used alongside pH, conductivity, and temperature sensors?

Yes. Pendotech pressure sensors can be combined with pH, conductivity, and temperature sensors within integrated monitoring and control systems to provide a complete view of bioprocess performance.

Can I integrate a single-use pressure sensor with my existing control system?

Yes. Pendotech single-use pressure sensors support integration with existing control and monitoring systems through PCS and compatible third-party platforms.

What pressure ranges are supported by Pendotech single-use pressure sensors?

Pendotech single-use pressure sensors are rated for use up to 75 psi, making them suitable for small- to medium-scale biopharmaceutical processes, including filtration and bioreactor applications.

Can these pressure sensors be used in a gamma sterilized single-use system?

Yes. Pendotech pressure sensors are compatible with both gamma irradiation and autoclaving for use in sterilized single-use systems.

What pressure sensor works with gamma sterilized tubing?

Pendotech single-use pressure sensors are designed to integrate with gamma-sterilized tubing assemblies commonly used in biopharmaceutical single-use systems.

Do these require calibration?

No. Every sensor is factory tested and shipped ready for use.

What controller do I need if I only have one or two sensors?

The PressureMAT™ System is ideal for small setups requiring pressure monitoring or alarm functionality.

What if I have multiple filtration steps and want automated control?

The Pendotech Process Control System (PCS) supports multi-sensor configurations and automated pressure management across multiple filtration steps.

Can they integrate with non-Pendotech pumps?

Yes. Pendotech single-use pressure sensors are pre-qualified for integration with various third-party pumps and monitoring systems.

How can I monitor pressure during TFF without adding hold-up volume?

Pendotech single-use pressure sensors enable inline pressure monitoring during TFF without introducing additional hold-up volume, preserving process efficiency and yield.

How do I configure the PressureMAT™ (PMAT) to start or stop a pump?

To use your PressureMAT™ (PMAT) to control a pump, configure its alarm outputs to trigger based on pressure thresholds.

How do I re-scale my PTR (Pressure Transmitter Reader)?

To re-scale your PTR, update the input/output range so the displayed or transmitted signal matches your sensor’s pressure range.

How do I connect my PressureMAT™ (PMAT) or scale to the PMAT GUI?

Connect the PMAT or scale to your PC via USB or serial cable and open the PMAT GUI software. In device setup, select or auto-detect the device, confirm the correct port, and verify settings. Assign channels and start logging to view real-time data.

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